The following players went from the Hanshin Tigers to the majors for an attempt at stardom. The year in brackets indicates their final season with Hanshin. This list does not include import players who started in America, made their way to Japan, and returned to MLB afterward. You can find many of them here.
Tsuyoshi Shinjo (2000) – to New York Mets
Keiichi Yabu (2004) – to Oakland Athletics
Kei Igawa (2006) – to New York Yankees
The following players left NPB for the majors and signed with Hanshin upon their return to Japan. The year in brackets indicates the year they joined Hanshin.
Hideki Irabu (2003) – from Texas Rangers
Kenji Johjima (2010) – from Seattle Mariners
Yoshinori Tateyama (2014) – from New York Yankees